University :Mansoura University |
Faculty :Faculty of Science |
Department :Chemistry Department |
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| 1- 1- Course data :- |
| | Code: | 48416 | | Course title: | Biochemistry -1 | | Year/Level: | رابعة كيمياء وكيمياء حيوية | | Program Title: | | | Specialization: | | | Teaching Hours: | Theoretical: | 4 | Tutorial: | | Practical: | 4 |
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| 2- 2- Course aims :- |
| - Introduce the basic concepts of immunochemistry and antibiotics.
- Introduce the basic concepts of nucleic acids.
- Study the physical and chemical properties of the major classes immunoglobulins.
- Study the different techniques for the determination of antibodies and nucleic acids in biological samples.
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| 3- 3- Course Learning Outcomes :- |
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| 4- 4- Course contents :- |
| | No | Topics | Week No. |
|---|
| 1 | Basic principles, Introduction, Definition of immuno system and Factors affecting the host-parasite relationship | | | 2 | Antigen-antibody reaction, infectivity and invasiveness virulence | | | 3 | Non-sepecific immuno reponse, immunogenicity and haptens | | | 4 | Immunoglobulins: structure and properties. | | | 5 | Complement systems ant its role in antigen-antibody reaction | | | 6 | Cell involved in the immuno response. Cellular interaction, role of T-cells in the immuno rsponse | | | 7 | Immunosuppretion and immunopotentiation. AIDS and immunology in transplantation | | | 8 | Basic principles, Introduction, Definition of nucleic acids | | | 9 | Chemistry of nuleosides and nuleotides , deoxy ribonucleotides and DNA and RNA structures | | | 10 | Metabolism of purine and pyrimidine nucleotides. | | | 11 | Nucleotides coenzymes synthesis, and purine and prymidine analogues | | | 12 | DNA organization and replication | | | 13 | Protein synthesis and genetic code and gene expression | | | 14 | clinical application:Lesch-Nyhan syndrome, Gout and immunodifficiency associated with defect of purines nucleotide metabolism | | | 15 | Practical: determination of blood groups, recognize the antigen/antibody reactions. | |
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| 5- 5- Teaching and learning methods :- |
| | S | Method |
|---|
| Lectures using data show and board | | Home works, reports and discussion groups | | Laboratory work |
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| 6- 6- Teaching and learning methods of disables :- |
| - None
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| 7- 7- Student assessment :- |
| - Timing |
| | No | Method | Week No. |
|---|
| 1 | Week # | 14 | | 2 | Week # | 14 | | 3 | Week # | 12 | | 4 | Week # | 4,8,12 | | 5 | Week # | 10 |
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| - Degree |
| | No | Method | Degree |
|---|
| 1 | Mid_term examination | 0 | | 2 | Final_term examination | 70 | | 3 | Oral examination | 10 | | 4 | Practical examination | 20 | | 5 | Semester work | 0 | | 6 | Other types of asessment | 0 | | Total | 100% |
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| 8- 8- List of books and references |
| | S | Reference | Type |
|---|
| 1 | Biohemistry Note provided by the lecturer | | | 2 | Harper’s Biochemistry, Twenty-second Edition, Middle East Edition | | | 3 | Textbook of biochemistry with clinical correlations, Thomas M. Devlin. Third Edn., wiely Liss, A John Wiley 7 Sons INC.,Publication (1992) | | | 4 | http://www.ncbi.nlm.nih.gov/pubmed/ | |
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| 9- 9- Matrix of knowledge and skills of the course |
| | S | Content | Study week |
|---|
| Basic principles, Introduction, Definition of immuno system and Factors affecting the host-parasite relationship | | | Antigen-antibody reaction, infectivity and invasiveness virulence | | | Non-sepecific immuno reponse, immunogenicity and haptens | | | Immunoglobulins: structure and properties. | | | Complement systems ant its role in antigen-antibody reaction | | | Cell involved in the immuno response. Cellular interaction, role of T-cells in the immuno rsponse | | | Immunosuppretion and immunopotentiation. AIDS and immunology in transplantation | | | Basic principles, Introduction, Definition of nucleic acids | | | Chemistry of nuleosides and nuleotides , deoxy ribonucleotides and DNA and RNA structures | | | Metabolism of purine and pyrimidine nucleotides. | | | Nucleotides coenzymes synthesis, and purine and prymidine analogues | | | DNA organization and replication | | | Protein synthesis and genetic code and gene expression | | | clinical application:Lesch-Nyhan syndrome, Gout and immunodifficiency associated with defect of purines nucleotide metabolism | | | Practical: determination of blood groups, recognize the antigen/antibody reactions. | |
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| Course Coordinator(s): - |
| - Mohamed Abd Elhafez Mohamed Ali Elfar
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| Head of department: - |
| Awad Ebrahim Ahmed Mohamed |
