University :Mansoura University |
Faculty :Faculty of Science |
Department :Chemistry Department |
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| 1- Course data :- |
| | Code: | 48415 | | Course title: | Chemistry -3 | | Year/Level: | رابعة كيمياء وكيمياء حيوية | | Program Title: | | | Specialization: | | | Teaching Hours: | Theoretical: | 4 | Tutorial: | 1 | Practical: | 8 |
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| 2- Course aims :- |
| - Introduce the basic information of natural products about different classes, nomenclature, biosynthesis, physiological and medicinal importance.
- Study the general methods used for structure elucidation of natural products and giving some representative examples.
- Acquiring the student the basic information of physical organic chemistry.
- Acquiring the student the skills of isolation and synthesizing of some natural products and organic compounds.
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| 3- Course Learning Outcomes :- |
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| 4- Course contents :- |
| | No | Topics | Week |
|---|
| 1 | Natural Products: · Definition, classification of natural products. | | | 2 | · Biosynthetic pathways (shikimic, mevalonic, acetate) of natural products. | | | 3 | · Terpenoids (definition, isoprene rule, exceptions of special isoprene rule, isolation, classification, methods of structure elucidation, examples for different terpenes) | | | 4 | · Terpenoids (structure elucidation and synthesis of selected terpenoids) | | | 5 | · Steroids (classes, stereochemistry, structure elucidation of selected steroids, sex hormones, adrenocortical hormones, hormone precursors) | | | 6 | · Alkaloids (introduction, classification, isolation, structure elucidation of selected alkaloids) | | | 7 | · Shikimates (C6-C1, C6-C2, C6-C3, compounds containing shikimate ring, structure elucidation of some flavonoids) | | | 8 | Practical: Synthesis and Applied organic experimental Chemistry | | | 9 | Physical Organic: · Aromatic electrophilic substitution. | | | 10 | Hyperconjugation | | | 11 | · Photochemistry - photodissociation reaction - photochemical reduction and oxidation - photochemical isomerisation of cis- & trans – unsaturated compounds - photochemical cyc1o–additions. | | | 12 | · Hammett equation –Taft equation - free radicals. | |
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| 5- Teaching and learning methods :- |
| | S | Method |
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| Lectures using data show and board | | Home works, reports and discussion groups | | Laboratory work |
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| 6- Teaching and learning methods of disables :- |
| - The same as normal students. Mental and audovisual disabilities are not allowed in Faculty of Science.
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| 7- Student assessment :- |
| A. Timing |
| | No | Method | Week |
|---|
| 1 | | 14 | | 2 | | 14 | | 3 | | 12 | | 4 | | 4,8,12 | | 5 | | 10 |
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| B. Degree |
| | No | Method | Degree |
|---|
| 1 | Mid_term examination | 0 | | 2 | Final_term examination | 70 | | 3 | Oral examination | 10 | | 4 | Practical examination | 20 | | 5 | Semester work | 0 | | 6 | Other types of asessment | 0 | | Total | 100% |
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| 8- List of books and references |
| | S | Item | Type |
|---|
| 1 | Physical Organic Chemistry | | | 2 | Chemistry of Natural Products | | | 3 | Morrison & Boyd, Organic Chemistry, Allyn & Bacon, Inc., Boston, 3rd Edn. (1973). | | | 4 | Finer,L., Organic Chemistry, 5th Edn., ELBS and Longman group Ltd. (1975). | | | 5 | Fessenden & Fessenden, Organic Chemistry, Willard Grant Press, Boston, Massachusetts, 2nd Edn. (1982). | | | 6 | http://en.wikipedia.org/wiki/Organic_chemistry | | | 7 | http://www.organic-chemistry.org/ | | | 8 | http://www.acdlabs.com/iupac/nomenclature/ | | | 9 | E-Course: http://osp.mans.edu.eg/mabdelmogib/nps.htm | |
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| 9- Matrix of knowledge and skills of the course |
| | S | Content | Study week |
|---|
| Natural Products: · Definition, classification of natural products. | | | · Biosynthetic pathways (shikimic, mevalonic, acetate) of natural products. | | | · Terpenoids (definition, isoprene rule, exceptions of special isoprene rule, isolation, classification, methods of structure elucidation, examples for different terpenes) | | | · Terpenoids (structure elucidation and synthesis of selected terpenoids) | | | · Steroids (classes, stereochemistry, structure elucidation of selected steroids, sex hormones, adrenocortical hormones, hormone precursors) | | | · Alkaloids (introduction, classification, isolation, structure elucidation of selected alkaloids) | | | · Shikimates (C6-C1, C6-C2, C6-C3, compounds containing shikimate ring, structure elucidation of some flavonoids) | | | Practical: Synthesis and Applied organic experimental Chemistry | | | Physical Organic: · Aromatic electrophilic substitution. | | | Hyperconjugation | | | · Photochemistry - photodissociation reaction - photochemical reduction and oxidation - photochemical isomerisation of cis- & trans – unsaturated compounds - photochemical cyc1o–additions. | | | · Hammett equation –Taft equation - free radicals. | |
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| Course Coordinator(s): - |
| - Mamdouh Abdel Megeed Mohamed Aldhtory
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| Head of department: - |
| Awad Ebrahim Ahmed Mohamed |
