University :Mansoura University |
Faculty :Faculty of Science |
Department :Chemistry Department |
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| 1- Course data :- |
| | Code: | 48315 | | Course title: | الانزيمات-كيمياء الموادالبروتينيةوالأحماض الأمنية | | Year/Level: | ثالثة كيمياء وكيمياء حيوية | | Program Title: | | | Specialization: | | | Teaching Hours: | Theoretical: | 4 | Tutorial: | | Practical: | 6 |
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| 2- Course aims :- |
| - Introduce the basic information of biochemistry.
- Introduce the basic information chemistry of proteins and enzymes.
- Study the physical and chemical properties of major classes of proteins and enzymes.
- Study of different physiological importance of proteins and enzymes.
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| 3- Course Learning Outcomes :- |
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| 4- Course contents :- |
| | No | Topics | Week |
|---|
| 1 | Enzymology; Chemical nature and Classification of enzymes. | | | 2 | Coenzymes factors affecting rate of enzyme action | | | 3 | Enzyme specificity; Types of active sites | | | 4 | Mechanism of enzyme actions | | | 5 | ?nhibition of enzymes: Competitive and non-competitive inhibitors | | | 6 | Allosteric control of enzyme activity | | | 7 | Clinical Applications: Enzymes as diagnostic tools in some diseases | | | 8 | Proteins & Amino acids; Basic principles, Introduction, Definition and Classification of amino acids | | | 9 | General reaction of amino acids:Transamination, Glutamate dehydrogenase, | | | 10 | Glycogenic and ketogenic amino acids | | | 11 | Urea cycle : Regulation and biological importance | | | 12 | Nitrogenous and sulphur derivatives of amino acid: Ceratine, Choline, Amines and polyamines, and Glutathione funtion. | | | 13 | Structure of proteins; Hemoglobin and myoglobin | | | 14 | Clinical Applications : Phenyl ketone urea, Parkinson’s dieases, Histidinemia and folic acid deficiency | | | 15 | Practical: Enzyme and protein functions , determination of enzyme in biological samples and investigate the reactions of amino acids. | |
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| 5- Teaching and learning methods :- |
| | S | Method |
|---|
| Lectures using data show and board | | Home works, reports and discussion groups | | Laboratory work |
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| 6- Teaching and learning methods of disables :- |
| - -
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| 7- Student assessment :- |
| A. Timing |
| | No | Method | Week |
|---|
| 1 | Final exam | 14 | | 2 | Oral exam | 14 | | 3 | Practical exam | 12 | | 4 | Quizzes | 4, 8, 12 | | 5 | Report | 10 |
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| B. Degree |
| | No | Method | Degree |
|---|
| 1 | Mid_term examination | 0 | | 2 | Final_term examination | 70 | | 3 | Oral examination | 10 | | 4 | Practical examination | 20 | | 5 | Semester work | 0 | | 6 | Other types of asessment | 0 | | Total | 100% |
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| 8- List of books and references |
| | S | Item | Type |
|---|
| 1 | Course Notes | | | 2 | Essential Books (Text Books)Harper’s Biochemistry, Twenty-second Edition, Middle East Edition | | | 3 | Recommended Books;Textbook of biochemistry with clinical correlations, Thomas M. Devlin. Third Edn., wiely Liss, A John Wiley 7 Sons INC.,Publication (1992) | | | 4 | Periodicals, Web Sites, http://www.ncbi.nlm.nih.gov/pubmed/ | |
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| 9- Matrix of knowledge and skills of the course |
| | S | Content | Study week |
|---|
| Enzymology; Chemical nature and Classification of enzymes. | | | Coenzymes factors affecting rate of enzyme action | | | Enzyme specificity; Types of active sites | | | Mechanism of enzyme actions | | | ?nhibition of enzymes: Competitive and non-competitive inhibitors | | | Allosteric control of enzyme activity | | | Clinical Applications: Enzymes as diagnostic tools in some diseases | | | Proteins & Amino acids; Basic principles, Introduction, Definition and Classification of amino acids | | | General reaction of amino acids:Transamination, Glutamate dehydrogenase, | | | Glycogenic and ketogenic amino acids | | | Urea cycle : Regulation and biological importance | | | Nitrogenous and sulphur derivatives of amino acid: Ceratine, Choline, Amines and polyamines, and Glutathione funtion. | | | Structure of proteins; Hemoglobin and myoglobin | | | Clinical Applications : Phenyl ketone urea, Parkinson’s dieases, Histidinemia and folic acid deficiency | | | Practical: Enzyme and protein functions , determination of enzyme in biological samples and investigate the reactions of amino acids. | |
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| Course Coordinator(s): - |
| - Mohamed Abd Elhafez Mohamed Ali Elfar
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| Head of department: - |
| Awad Ebrahim Ahmed Mohamed |
